Solgar Boron
£10.50
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Natural Choice
4 Market Pl, Knaresborough, United Kingdom, HG5 8AGUsually ready in 24 hours
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Demeter
15 Welles Street, Sandbach, United Kingdom, CW11 1GTSold out
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Various boron-containing drugs have been approved for clinical use over the past two decades, and more are currently in clinical trials. The increasing interest in boron-containing compounds is due to their unique binding properties to biological targets; for example, boron substitution can be used to modulate biological activity, pharmacokinetic properties, and drug resistance. In this perspective, we aim to comprehensively review the current status of boron compounds in drug discovery, focusing especially on progress from 2015 to December 2020. We classify these compounds into groups showing anticancer, antibacterial, antiviral, antiparasitic and other activities, and discuss the biological targets associated with each activity, as well as potential future developments.
Graphical abstract
Boron derivatives are playing an increasingly important role on drug discovery campaigns. Here, we reviewed the use and pharmacological properties of boronic acids as therapeutic agents for various diseases
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Solgar Boron
£10.50